STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lepBSignal peptidase I; Identified by similarity to SP:P00803; match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family. (449 aa)    
Predicted Functional Partners:
FSU_2125
Putative lipoprotein.
 
     0.836
FSU_2398
Tetratricopeptide repeat protein; Identified by match to protein family HMM PF00515.
 
  
 0.823
FSU_2126
Putative DnaQ family exonuclease/DinG family helicase; Identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573.
  
    0.766
FSU_2123
DNA-binding response regulator; Identified by similarity to SP:P33356; match to protein family HMM PF00072; match to protein family HMM PF04397.
  
    0.754
FSU_2120
FG-GAP repeat protein; Identified by match to protein family HMM PF01839.
 
     0.734
FSU_2122
Putative lipoprotein.
       0.722
FSU_2121
carF domain protein; Identified by similarity to GB:AAD38234.1; match to protein family HMM PF03781.
       0.691
secDF
Protein-export membrane protein SecDF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
 
  
 0.683
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
    0.679
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
 
 0.658
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.