STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FSU_2220Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583. (162 aa)    
Predicted Functional Partners:
FSU_2219
Transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
       0.734
metS
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
    
  0.569
FSU_1626
Identified by match to protein family HMM PF01564.
     
  0.567
bioA
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00508; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.521
hisH
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
    
  0.520
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
    
  0.519
FSU_2188
4-carboxymuconolactone decarboxylase domain protein; Identified by match to protein family HMM PF02627.
    
 0.508
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
    
  0.496
FSU_3136
Conserved hypothetical protein; Identified by similarity to GB:AAO76206.1.
    
  0.474
FSU_0560
Conserved hypothetical protein; Identified by similarity to GB:CAE27785.1; match to protein family HMM PF07883.
    
 0.454
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
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