| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FSU_2348 | hisA | FSU_2348 | FSU_2783 | Putative lipoprotein. | 1-(5-phosphoribosyl)-5-((5'-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase; Identified by similarity to SP:P40545; match to protein family HMM PF00977; match to protein family HMM TIGR02129; Belongs to the HisA/HisF family. | 0.707 |
| FSU_2348 | hisB | FSU_2348 | FSU_3097 | Putative lipoprotein. | Imidazoleglycerol-phosphate dehydratase; Identified by similarity to SP:O34683; match to protein family HMM PF00475. | 0.640 |
| FSU_2348 | hisD | FSU_2348 | FSU_0009 | Putative lipoprotein. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.566 |
| FSU_2348 | hisF | FSU_2348 | FSU_2822 | Putative lipoprotein. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.800 |
| FSU_2348 | hisH | FSU_2348 | FSU_1063 | Putative lipoprotein. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.718 |
| FSU_2348 | hisI | FSU_2348 | FSU_0317 | Putative lipoprotein. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.643 |
| FSU_2348 | metH | FSU_2348 | FSU_1627 | Putative lipoprotein. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.653 |
| FSU_2348 | metXW | FSU_2348 | FSU_0385 | Putative lipoprotein. | Homoserine O-acetyltransferase/methionine biosynthesis protein; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.627 |
| FSU_2348 | serC | FSU_2348 | FSU_1007 | Putative lipoprotein. | Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.611 |
| FSU_2348 | trpCF | FSU_2348 | FSU_0580 | Putative lipoprotein. | Indole-3-glycerol phosphate synthase/N-(5'-phosphoribosyl)anthranilate isomerase; Identified by similarity to SP:O25867; match to protein family HMM PF00218; match to protein family HMM PF00697; Belongs to the TrpF family. | 0.644 |
| hisA | FSU_2348 | FSU_2783 | FSU_2348 | 1-(5-phosphoribosyl)-5-((5'-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase; Identified by similarity to SP:P40545; match to protein family HMM PF00977; match to protein family HMM TIGR02129; Belongs to the HisA/HisF family. | Putative lipoprotein. | 0.707 |
| hisA | hisB | FSU_2783 | FSU_3097 | 1-(5-phosphoribosyl)-5-((5'-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase; Identified by similarity to SP:P40545; match to protein family HMM PF00977; match to protein family HMM TIGR02129; Belongs to the HisA/HisF family. | Imidazoleglycerol-phosphate dehydratase; Identified by similarity to SP:O34683; match to protein family HMM PF00475. | 0.958 |
| hisA | hisD | FSU_2783 | FSU_0009 | 1-(5-phosphoribosyl)-5-((5'-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase; Identified by similarity to SP:P40545; match to protein family HMM PF00977; match to protein family HMM TIGR02129; Belongs to the HisA/HisF family. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.952 |
| hisA | hisF | FSU_2783 | FSU_2822 | 1-(5-phosphoribosyl)-5-((5'-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase; Identified by similarity to SP:P40545; match to protein family HMM PF00977; match to protein family HMM TIGR02129; Belongs to the HisA/HisF family. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.978 |
| hisA | hisH | FSU_2783 | FSU_1063 | 1-(5-phosphoribosyl)-5-((5'-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase; Identified by similarity to SP:P40545; match to protein family HMM PF00977; match to protein family HMM TIGR02129; Belongs to the HisA/HisF family. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.978 |
| hisA | hisI | FSU_2783 | FSU_0317 | 1-(5-phosphoribosyl)-5-((5'-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase; Identified by similarity to SP:P40545; match to protein family HMM PF00977; match to protein family HMM TIGR02129; Belongs to the HisA/HisF family. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.978 |
| hisA | trpCF | FSU_2783 | FSU_0580 | 1-(5-phosphoribosyl)-5-((5'-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase; Identified by similarity to SP:P40545; match to protein family HMM PF00977; match to protein family HMM TIGR02129; Belongs to the HisA/HisF family. | Indole-3-glycerol phosphate synthase/N-(5'-phosphoribosyl)anthranilate isomerase; Identified by similarity to SP:O25867; match to protein family HMM PF00218; match to protein family HMM PF00697; Belongs to the TrpF family. | 0.782 |
| hisB | FSU_2348 | FSU_3097 | FSU_2348 | Imidazoleglycerol-phosphate dehydratase; Identified by similarity to SP:O34683; match to protein family HMM PF00475. | Putative lipoprotein. | 0.640 |
| hisB | hisA | FSU_3097 | FSU_2783 | Imidazoleglycerol-phosphate dehydratase; Identified by similarity to SP:O34683; match to protein family HMM PF00475. | 1-(5-phosphoribosyl)-5-((5'-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase; Identified by similarity to SP:P40545; match to protein family HMM PF00977; match to protein family HMM TIGR02129; Belongs to the HisA/HisF family. | 0.958 |
| hisB | hisD | FSU_3097 | FSU_0009 | Imidazoleglycerol-phosphate dehydratase; Identified by similarity to SP:O34683; match to protein family HMM PF00475. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.998 |