pyrH protein (Fibrobacter succinogenes) - STRING interaction network

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pyrH

UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (235 aa)

Predicted Functional Partners:

frr

0.991

tsf

0.967

rpsJ

0.829

tig

0.816

rplA

0.799

ndk

0.787

pyrF

0.778

pyrR

0.769

guaA

0.767

trmD

0.766

Your Current Organism:

Fibrobacter succinogenes

NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
frr	guaA	FSU_2353	FSU_0249	Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888.	0.521
frr	pyrH	FSU_2353	FSU_2350	Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.991
frr	rplA	FSU_2353	FSU_1737	Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.976
frr	rpsJ	FSU_2353	FSU_1891	Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	0.918
frr	tig	FSU_2353	FSU_1857	Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.900
frr	tsf	FSU_2353	FSU_1393	Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.	0.974
guaA	frr	FSU_0249	FSU_2353	GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888.	Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	0.521
guaA	ndk	FSU_0249	FSU_3059	GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.503
guaA	pyrF	FSU_0249	FSU_2138	GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888.	Orotidine 5`-phosphate decarboxylase; Identified by similarity to SP:Q9P9M3; match to protein family HMM PF00215; match to protein family HMM TIGR02127.	0.476
guaA	pyrH	FSU_0249	FSU_2350	GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888.	UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.767
guaA	rplA	FSU_0249	FSU_1737	GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888.	Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.926
guaA	rpsJ	FSU_0249	FSU_1891	GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888.	Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	0.624
guaA	tig	FSU_0249	FSU_1857	GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.782
guaA	trmD	FSU_0249	FSU_2963	GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888.	tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.	0.503
guaA	tsf	FSU_0249	FSU_1393	GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888.	Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.	0.741
ndk	guaA	FSU_3059	FSU_0249	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	GMP synthase; Identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00888.	0.503
ndk	pyrH	FSU_3059	FSU_2350	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.787
ndk	rplA	FSU_3059	FSU_1737	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.453
ndk	rpsJ	FSU_3059	FSU_1891	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	0.989
ndk	tig	FSU_3059	FSU_1857	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.863