STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
tsaDMetalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (335 aa)    
Predicted Functional Partners:
FSU_0448
Peptidase, M22 family; Identified by match to protein family HMM PF00814; match to protein family HMM TIGR03725.
  
 
 0.921
FSU_0742
ATPase, YjeE family; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150.
  
 
 0.885
FSU_2424
Conserved hypothetical protein; Identified by similarity to GB:AAM25361.1.
       0.789
FSU_2422
Conserved domain protein; Identified by similarity to GB:BAC44739.1.
       0.727
FSU_2427
Putative DNA polymerase III, delta prime subunit.
 
   
 0.676
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
  
 0.668
FSU_3177
Identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057; Belongs to the SUA5 family.
 
 0.658
gpsA
Glycerol-3-phosphate dehydrogenase [NAD(P)+ ]; Identified by similarity to SP:P46919; match to protein family HMM PF01210; match to protein family HMM PF07479; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
      0.609
FSU_0829
Sua5/YciO/YrdC/YwlC family/SUA5 domain protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
  
 0.600
FSU_2425
Putative cell division ABC transporter, permease protein FtsX; Identified by similarity to SP:P10122; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
       0.593
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
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