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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FSU_2469ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (468 aa)    
Predicted Functional Partners:
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
   0.757
crcB
crcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
  
    0.703
FSU_2468
Esterase domain protein; Identified by similarity to GB:CAC85738.1.
       0.519
FSU_2471
ATP-binding protein, Mrp/Nbp35 family; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
       0.477
FSU_2472
Conserved hypothetical protein; Identified by similarity to PIR:E83358.
       0.477
FSU_2267
Putative acetyl xylan esterase; Identified by similarity to GB:AAC14690.1; match to protein family HMM PF03422; match to protein family HMM PF03629.
  
     0.460
FSU_0054
Putative acetylxylan esterase; Identified by similarity to GB:AAC14690.1; match to protein family HMM PF03629.
  
     0.439
FSU_2456
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.
  
     0.433
FSU_2864
Putative acetyl xylan esterase; Identified by similarity to GB:AAC14690.1; match to protein family HMM PF03629.
  
     0.411
FSU_0145
Arabinosidase-like protein; Identified by similarity to GB:AAB03089.1.
  
     0.408
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
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