Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FSU_2555Oxidoreductase, aldo/keto reductase family; Identified by match to protein family HMM PF00248. (279 aa)    
Predicted Functional Partners:
FSU_1921
Glyoxalase family protein; Identified by similarity to GB:AAP27170.1; match to protein family HMM PF00903.
   
 0.550
bdhA
NADH-dependent butanol dehydrogenase A; Identified by similarity to SP:Q04944; match to protein family HMM PF00465.
  
 
 0.523
ald
Aldehyde dehydrogenase; Identified by similarity to SP:P46329; match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.
   
 0.496
FSU_0977
HAD-superfamily hydrolase, subfamily IIA; Identified by match to protein family HMM PF00702.
  
 
 0.469
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 0.456
trpCF
Indole-3-glycerol phosphate synthase/N-(5'-phosphoribosyl)anthranilate isomerase; Identified by similarity to SP:O25867; match to protein family HMM PF00218; match to protein family HMM PF00697; Belongs to the TrpF family.
     
 0.453
FSU_2554
Cation diffusion facilitator family transporter; Identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
      0.428
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
    
  0.411
FSU_0310
Pyridoxal-phosphate dependent TrpB family enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
  0.408
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
  0.408
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.