STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FSU_2557Putative 4-hydroxy-2-oxovalerate aldolase; Identified by match to protein family HMM PF00682. (313 aa)    
Predicted Functional Partners:
FSU_2014
Putative para-aminobenzoate synthetase; Identified by similarity to SP:P28820; match to protein family HMM PF00425.
  
 
 0.838
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
  
 
 0.796
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
  
 0.785
leuD
3-isopropylmalate dehydratase, small subunit; Identified by similarity to SP:P30126; match to protein family HMM PF00694; match to protein family HMM TIGR00171; Belongs to the LeuD family.
  
  
 0.783
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.780
ilvD
Dihydroxy-acid dehydratase; Identified by similarity to SP:P05791; match to protein family HMM PF00920; match to protein family HMM TIGR00110; Belongs to the IlvD/Edd family.
  
  
 0.762
FSU_2556
Conserved domain protein; Identified by similarity to GB:AAO52466.1; match to protein family HMM TIGR02148.
       0.762
ilvE
Branched-chain-amino-acid transaminase; Identified by similarity to GB:AAF64593.1; match to protein family HMM PF01063; match to protein family HMM TIGR01123.
  
 
 0.587
kdsB
3-deoxy-manno-octulosonate cytidylyltransferase; Identified by similarity to SP:P04951; match to protein family HMM PF02348.
      0.584
ilvN
Acetolactate synthase, small subunit; Identified by match to protein family HMM PF01842; match to protein family HMM TIGR00119.
  
  
 0.575
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
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