STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
relAGTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (714 aa)    
Predicted Functional Partners:
FSU_1663
HD domain protein; Identified by match to protein family HMM PF01966.
  
  
 
0.926
FSU_2714
Phosphatase, Ppx/GppA family; Identified by match to protein family HMM PF02541.
  
 
 0.926
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.911
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.908
FSU_1662
RelA/SpoT domain protein; Identified by match to protein family HMM PF04607.
     
 0.907
nrdD
Anaerobic ribonucleoside-triphosphate reductase; Identified by similarity to SP:P07071; match to protein family HMM TIGR02487.
     
  0.900
FSU_2995
Adenylate/guanylate cyclase domain protein; Identified by match to protein family HMM PF00211; match to protein family HMM PF05226.
     
  0.900
ribA
Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
  0.819
rplV
Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
  
 
   0.810
rplR
Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
  
 
   0.805
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
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