Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FSU_2900Chaperonin, 33 kDa family; Identified by match to protein family HMM PF01430. (295 aa)    
Predicted Functional Partners:
thiJ
4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme; Identified by similarity to SP:Q46948; match to protein family HMM PF01965; match to protein family HMM TIGR01383.
     
 0.606
lon
Identified by similarity to SP:P08177; match to protein family HMM PF00004; match to protein family HMM PF05362; match to protein family HMM PF07728; match to protein family HMM TIGR00763.
  
  
 0.561
thrH
Phosphoserine phosphatase/homoserine phosphotransferase protein; Identified by similarity to GB:CAA07580.1; match to protein family HMM PF00702; match to protein family HMM TIGR02137.
       0.520
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
   
  
 0.493
htpG
Heat shock protein HtpG; Molecular chaperone. Has ATPase activity.
   
  
 0.435
FSU_2424
Conserved hypothetical protein; Identified by similarity to GB:AAM25361.1.
  
    0.413
coaX
Putative transcriptional activator; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
  
    0.406
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
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