STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
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[Homology]
Score
ppnKInorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (314 aa)    
Predicted Functional Partners:
FSU_3130
Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Identified by similarity to SP:P20691.
     
 0.796
FSU_3129
Prephenate dehydrogenase; Identified by similarity to SP:P20692; match to protein family HMM PF01842; match to protein family HMM PF02153.
       0.736
FSU_3128
Chorismate mutase; Identified by similarity to SP:P07023; match to protein family HMM PF01817.
  
  
 0.734
FSU_0004
NAD+ synthetase, glutamine-dependent; Identified by match to protein family HMM PF02540; match to protein family HMM TIGR00552; Belongs to the NAD synthetase family.
    
 0.705
nadE
NAD+ synthetase, glutamine-dependent; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.705
FSU_3127
Mechanosensitive ion channel family protein; Identified by match to protein family HMM PF00924.
  
    0.653
nadD
Putative nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.602
maeB
NADP-dependent malic enzyme; Identified by similarity to SP:P76558; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949.
   
 0.574
cobB
cobB protein; Identified by similarity to GB:AAC78722.1; match to protein family HMM PF02146; Belongs to the sirtuin family. Class III subfamily.
  
 
 0.563
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
    
 0.542
Your Current Organism:
Fibrobacter succinogenes
NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85
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