node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FSU_2603 | FSU_3139 | FSU_2603 | FSU_3139 | Putative membrane protein; Identified by match to protein family HMM PF00892. | Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.408 |
FSU_3138 | FSU_3139 | FSU_3138 | FSU_3139 | Radical SAM domain protein; Identified by similarity to GB:AAP29339.1; match to protein family HMM PF04055. | Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.773 |
FSU_3138 | FSU_3141 | FSU_3138 | FSU_3141 | Radical SAM domain protein; Identified by similarity to GB:AAP29339.1; match to protein family HMM PF04055. | Putative membrane protein; Identified by match to protein family HMM PF05154. | 0.773 |
FSU_3138 | FSU_3142 | FSU_3138 | FSU_3142 | Radical SAM domain protein; Identified by similarity to GB:AAP29339.1; match to protein family HMM PF04055. | Putative lipoprotein. | 0.564 |
FSU_3138 | FSU_3143 | FSU_3138 | FSU_3143 | Radical SAM domain protein; Identified by similarity to GB:AAP29339.1; match to protein family HMM PF04055. | Hypothetical protein; Identified by glimmer; putative. | 0.539 |
FSU_3138 | rdgB | FSU_3138 | FSU_3140 | Radical SAM domain protein; Identified by similarity to GB:AAP29339.1; match to protein family HMM PF04055. | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.776 |
FSU_3139 | FSU_2603 | FSU_3139 | FSU_2603 | Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Putative membrane protein; Identified by match to protein family HMM PF00892. | 0.408 |
FSU_3139 | FSU_3138 | FSU_3139 | FSU_3138 | Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Radical SAM domain protein; Identified by similarity to GB:AAP29339.1; match to protein family HMM PF04055. | 0.773 |
FSU_3139 | FSU_3141 | FSU_3139 | FSU_3141 | Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Putative membrane protein; Identified by match to protein family HMM PF05154. | 0.776 |
FSU_3139 | FSU_3142 | FSU_3139 | FSU_3142 | Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Putative lipoprotein. | 0.564 |
FSU_3139 | FSU_3143 | FSU_3139 | FSU_3143 | Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Hypothetical protein; Identified by glimmer; putative. | 0.539 |
FSU_3139 | FSU_3227 | FSU_3139 | FSU_3227 | Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 4Fe-4S binding domain protein; Identified by match to protein family HMM PF00037. | 0.479 |
FSU_3139 | panC | FSU_3139 | FSU_2994 | Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.466 |
FSU_3139 | proS | FSU_3139 | FSU_0165 | Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] | 0.517 |
FSU_3139 | rdgB | FSU_3139 | FSU_3140 | Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.777 |
FSU_3139 | truA | FSU_3139 | FSU_1108 | Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.402 |
FSU_3141 | FSU_3138 | FSU_3141 | FSU_3138 | Putative membrane protein; Identified by match to protein family HMM PF05154. | Radical SAM domain protein; Identified by similarity to GB:AAP29339.1; match to protein family HMM PF04055. | 0.773 |
FSU_3141 | FSU_3139 | FSU_3141 | FSU_3139 | Putative membrane protein; Identified by match to protein family HMM PF05154. | Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.776 |
FSU_3141 | FSU_3142 | FSU_3141 | FSU_3142 | Putative membrane protein; Identified by match to protein family HMM PF05154. | Putative lipoprotein. | 0.564 |
FSU_3141 | FSU_3143 | FSU_3141 | FSU_3143 | Putative membrane protein; Identified by match to protein family HMM PF05154. | Hypothetical protein; Identified by glimmer; putative. | 0.539 |