rnhB protein (Fibrobacter succinogenes) - STRING interaction network

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rnhB

Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (247 aa)

Predicted Functional Partners:

queH

0.899

dnaN

0.885

polA

0.869

FSU_1321

0.849

lpxB

0.846

recQ

0.791

purN

0.789

FSU_0051

0.766

thyA

0.766

FSU_0592

0.755

Your Current Organism:

Fibrobacter succinogenes

NCBI taxonomy Id: 59374
Other names: F. succinogenes subsp. succinogenes S85, Fibrobacter succinogenes S85, Fibrobacter succinogenes subsp. succinogenes S85

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FSU_0051	FSU_0592	FSU_0051	FSU_0592	acyltransferase/AMP-binding enzyme; Identified by match to protein family HMM PF00501; match to protein family HMM PF01553; match to protein family HMM PF07690.	acyltransferase/AMP-binding enzyme; Identified by match to protein family HMM PF00501; match to protein family HMM PF01553; match to protein family HMM PF07690.	0.685
FSU_0051	rnhB	FSU_0051	FSU_3275	acyltransferase/AMP-binding enzyme; Identified by match to protein family HMM PF00501; match to protein family HMM PF01553; match to protein family HMM PF07690.	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.766
FSU_0051	thyA	FSU_0051	FSU_3079	acyltransferase/AMP-binding enzyme; Identified by match to protein family HMM PF00501; match to protein family HMM PF01553; match to protein family HMM PF07690.	Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.	0.431
FSU_0592	FSU_0051	FSU_0592	FSU_0051	acyltransferase/AMP-binding enzyme; Identified by match to protein family HMM PF00501; match to protein family HMM PF01553; match to protein family HMM PF07690.	acyltransferase/AMP-binding enzyme; Identified by match to protein family HMM PF00501; match to protein family HMM PF01553; match to protein family HMM PF07690.	0.685
FSU_0592	rnhB	FSU_0592	FSU_3275	acyltransferase/AMP-binding enzyme; Identified by match to protein family HMM PF00501; match to protein family HMM PF01553; match to protein family HMM PF07690.	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.755
FSU_1321	dnaN	FSU_1321	FSU_1802	ATP-dependent DNA helicase, RecQ family/UvrD/REP helicase domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00580; match to protein family HMM TIGR00614.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.924
FSU_1321	polA	FSU_1321	FSU_1227	ATP-dependent DNA helicase, RecQ family/UvrD/REP helicase domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00580; match to protein family HMM TIGR00614.	DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.964
FSU_1321	recQ	FSU_1321	FSU_1079	ATP-dependent DNA helicase, RecQ family/UvrD/REP helicase domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00580; match to protein family HMM TIGR00614.	ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM PF09382; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389.	0.813
FSU_1321	rnhB	FSU_1321	FSU_3275	ATP-dependent DNA helicase, RecQ family/UvrD/REP helicase domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00580; match to protein family HMM TIGR00614.	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.849
dnaN	FSU_1321	FSU_1802	FSU_1321	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	ATP-dependent DNA helicase, RecQ family/UvrD/REP helicase domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00580; match to protein family HMM TIGR00614.	0.924
dnaN	polA	FSU_1802	FSU_1227	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.991
dnaN	recQ	FSU_1802	FSU_1079	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM PF09382; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389.	0.602
dnaN	rnhB	FSU_1802	FSU_3275	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.885
dnaN	thyA	FSU_1802	FSU_3079	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.	0.844
lpxB	rnhB	FSU_1121	FSU_3275	lipid-A-disaccharide synthetase; Identified by similarity to SP:P10441; match to protein family HMM PF02684; Belongs to the LpxB family.	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.846
polA	FSU_1321	FSU_1227	FSU_1321	DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	ATP-dependent DNA helicase, RecQ family/UvrD/REP helicase domain protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00580; match to protein family HMM TIGR00614.	0.964
polA	dnaN	FSU_1227	FSU_1802	DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.991
polA	recQ	FSU_1227	FSU_1079	DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM PF09382; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389.	0.930
polA	rnhB	FSU_1227	FSU_3275	DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.869
polA	thyA	FSU_1227	FSU_3079	DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.	0.541