Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB01283.1PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 2 family. (461 aa)    
Predicted Functional Partners:
AGB03490.1
PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; TIGRFAM: phosphoglucosamine mutase.
 
 
 0.952
AGB02123.1
Nucleoside-diphosphate-sugar pyrophosphorylase family protein; PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide (three repeats).
  
 
 0.943
AGB01501.1
PFAM: NAD dependent epimerase/dehydratase family.
 
 
 0.939
AGB01411.1
Thermophilic glucose-6-phosphate isomerase-like enzyme; PFAM: Glucose-6-phosphate isomerase (GPI); manually curated.
    
  0.926
fbp
Fructose-1,6-bisphosphatase; PFAM: Fructose-1-6-bisphosphatase.
   
 0.921
AGB01503.1
Nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase.
 
 
 0.916
AGB01186.1
Putative UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; TIGRFAM: nucleotide sugar dehydrogenase.
 
 
 0.915
glmS
Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.915
AGB03842.1
PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide (three repeats); TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; glucose-1-phosphate thymidylylransferase, long form.
  
 
 0.886
AGB03843.1
PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide (three repeats); TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; glucose-1-phosphate thymidylylransferase, long form.
  
 
 0.886
Your Current Organism:
Methanoregula formicica
NCBI taxonomy Id: 593750
Other names: M. formicica SMSP, Methanomicrobiales archaeon SMSP, Methanoregula formicica SMSP, Methanoregula formicica str. SMSP, Methanoregula formicica strain SMSP
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