Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AGB01572.1Putative Co/Zn/Cd cation transporter; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter. (308 aa)    
Predicted Functional Partners:
AGB03170.1
PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; Belongs to the LDH/MDH superfamily.
  
    0.664
AGB03685.1
PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; Belongs to the LDH/MDH superfamily.
  
    0.664
AGB01571.1
PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter.
 
    
0.547
rnj
Putative hydrolase of the metallo-beta-lactamase superfamily; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
 
     0.463
AGB01779.1
NhaP-type Na+(K+)/H+ antiporter; PFAM: Sodium/hydrogen exchanger family; TrkA-C domain.
 
   
 0.453
AGB01564.1
Putative dioxygenase; PFAM: Memo-like protein; Belongs to the MEMO1 family.
 
    0.441
gltX
glutamyl-tRNA synthetase, archaeal and eukaryotic family; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
  
    0.435
AGB02988.1
PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; Bacterial extracellular solute-binding proteins, family 3; TIGRFAM: PAS domain S-box.
 
  
 0.432
AGB03705.1
Co/Zn/Cd efflux system component; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter.
 
 
 0.426
AGB01569.1
Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
     
 0.420
Your Current Organism:
Methanoregula formicica
NCBI taxonomy Id: 593750
Other names: M. formicica SMSP, Methanomicrobiales archaeon SMSP, Methanoregula formicica SMSP, Methanoregula formicica str. SMSP, Methanoregula formicica strain SMSP
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.