Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nusANusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family. (147 aa)    
Predicted Functional Partners:
AGB02077.1
DNA-directed RNA polymerase, beta subunit/140 kD subunit; PFAM: RNA polymerase Rpb2, domain 3; RNA polymerase beta subunit; RNA polymerase Rpb2, domain 2; Belongs to the RNA polymerase beta chain family.
 
 
 0.959
rpoD
DNA-directed RNA polymerase, alpha subunit/40 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.957
rps7
Ribosomal protein S7/S5; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.
  
 
 0.953
spt5
Ribosomal protein L24p/L26e, archaeal; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
 
 0.951
rps10
Ribosomal protein S10/S20; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
 
 0.951
rpl24
Ribosomal protein L24p/L26e, archaeal/eukaryotic; Located at the polypeptide exit tunnel on the outside of the subunit.
 
   0.948
AGB02078.1
DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.947
fusA
Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]
  
 
 0.946
rps2
PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein Sa(cytosolic)/S2(archaeal); Belongs to the universal ribosomal protein uS2 family.
  
 
 0.944
rpl22
Ribosomal protein L22/L17; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
 
   0.943
Your Current Organism:
Methanoregula formicica
NCBI taxonomy Id: 593750
Other names: M. formicica SMSP, Methanomicrobiales archaeon SMSP, Methanoregula formicica SMSP, Methanoregula formicica str. SMSP, Methanoregula formicica strain SMSP
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