Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB01866.1Putative transcriptional regulator; PFAM: Helix-turn-helix. (112 aa)    
Predicted Functional Partners:
fdhD
Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
     0.805
AGB01865.1
TIGR00268 family protein; PFAM: Asparagine synthase; TIGRFAM: TIGR00268 family protein.
       0.798
AGB03680.1
Putative transcriptional regulator; PFAM: Helix-turn-helix.
  
     0.690
AGB01868.1
PFAM: ThiS family; TIGRFAM: MoaD family protein, archaeal.
 
     0.603
AGB01869.1
Dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis; PFAM: MoeZ/MoeB domain; ThiF family.
 
     0.600
AGB01867.1
Molybdopterin converting factor, large subunit; PFAM: MoaE protein.
       0.519
AGB03582.1
Hypothetical protein.
 
     0.517
AGB01291.1
Putative methanogenesis marker protein 17; PFAM: Uncharacterized protein conserved in archaea (DUF2113); TIGRFAM: putative methanogenesis marker protein 17.
  
     0.515
AGB03604.1
PFAM: Radical SAM superfamily; TIGRFAM: putative peptide-modifying radical SAM enzyme, Mhun_1560 family; radical SAM additional 4Fe4S-binding domain.
  
     0.504
AGB03588.1
Putative methanogenesis marker protein 11; PFAM: Domain of unknown function (DUF1743); TIGRFAM: putative methanogenesis marker protein 11.
 
     0.472
Your Current Organism:
Methanoregula formicica
NCBI taxonomy Id: 593750
Other names: M. formicica SMSP, Methanomicrobiales archaeon SMSP, Methanoregula formicica SMSP, Methanoregula formicica str. SMSP, Methanoregula formicica strain SMSP
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