Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB01869.1Dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis; PFAM: MoeZ/MoeB domain; ThiF family. (252 aa)    
Predicted Functional Partners:
AGB01868.1
PFAM: ThiS family; TIGRFAM: MoaD family protein, archaeal.
 
 0.994
iscS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
   
 0.988
AGB03458.1
PFAM: ThiS family; TIGRFAM: MoaD family protein, archaeal.
  
 0.974
AGB01867.1
Molybdopterin converting factor, large subunit; PFAM: MoaE protein.
 
 0.960
rpl40e
PFAM: Ribosomal L40e family; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.929
AGB02938.1
PFAM: Protein kinase domain.
  
 0.921
AGB01862.1
Sulfur transfer protein involved in thiamine biosynthesis; PFAM: ThiS family.
  
 
 0.909
AGB03457.1
Dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis; PFAM: MoeZ/MoeB domain; ThiF family.
  
  
 
0.901
alaS
alanine--tRNA ligase/alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
 0.836
AGB03459.1
Molybdopterin converting factor, large subunit; PFAM: MoaE protein.
 
 0.832
Your Current Organism:
Methanoregula formicica
NCBI taxonomy Id: 593750
Other names: M. formicica SMSP, Methanomicrobiales archaeon SMSP, Methanoregula formicica SMSP, Methanoregula formicica str. SMSP, Methanoregula formicica strain SMSP
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