Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AGB01930.1Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (570 aa)    
Predicted Functional Partners:
AGB01927.1
PFAM: Methyl-coenzyme M reductase beta subunit, C-terminal domain; Methyl-coenzyme M reductase beta subunit, N-terminal domain; TIGRFAM: methyl-coenzyme M reductase, beta subunit.
 
 0.999
AGB01929.1
PFAM: Methyl-coenzyme M reductase gamma subunit; TIGRFAM: methyl-coenzyme M reductase, gamma subunit.
 
 0.999
AGB03597.1
PFAM: Methyl-coenzyme M reductase beta subunit, C-terminal domain; Methyl-coenzyme M reductase beta subunit, N-terminal domain; TIGRFAM: methyl-coenzyme M reductase, beta subunit.
 
 0.999
AGB03600.1
PFAM: Methyl-coenzyme M reductase gamma subunit; TIGRFAM: methyl-coenzyme M reductase, gamma subunit.
 
 0.999
AGB01928.1
PFAM: Methyl-coenzyme M reductase operon protein D; TIGRFAM: methyl-coenzyme M reductase operon protein D.
 
 
 0.996
AGB03599.1
PFAM: Methyl-coenzyme M reductase operon protein C; TIGRFAM: methyl-coenzyme M reductase I operon protein C.
 
 
 0.994
AGB03598.1
PFAM: Methyl-coenzyme M reductase operon protein D; TIGRFAM: methyl-coenzyme M reductase operon protein D.
 
 
 0.984
AGB01290.1
Putative methanogenesis marker protein 7; PFAM: Methyl-coenzyme M reductase operon protein C; TIGRFAM: putative methanogenesis marker protein 7.
 
 
   0.937
AGB01291.1
Putative methanogenesis marker protein 17; PFAM: Uncharacterized protein conserved in archaea (DUF2113); TIGRFAM: putative methanogenesis marker protein 17.
 
 
 
 0.933
AGB02356.1
Putative methanogenesis marker protein 10; PFAM: Radical SAM superfamily; Protein of unknown function (DUF512); TIGRFAM: putative methanogenesis marker protein 10.
 
 
 
 0.933
Your Current Organism:
Methanoregula formicica
NCBI taxonomy Id: 593750
Other names: M. formicica SMSP, Methanomicrobiales archaeon SMSP, Methanoregula formicica SMSP, Methanoregula formicica str. SMSP, Methanoregula formicica strain SMSP
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.