Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (266 aa)    
Predicted Functional Partners:
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 0.999
AGB01318.1
Hypothetical protein; PFAM: Archaeal phosphomethylpyrimidine kinase.
    
 0.914
AGB02800.1
Hypothetical protein; PFAM: Archaeal phosphomethylpyrimidine kinase.
    
 0.914
ubiX
Polyprenyl p-hydroxybenzoate/phenylacrylic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
    
  0.902
AGB01502.1
ADP-ribose pyrophosphatase; PFAM: NUDIX domain.
    
  0.901
AGB03821.1
NTP pyrophosphohydrolase; PFAM: NUDIX domain.
    
  0.901
AGB02015.1
TIGRFAM: DNA ligase D, 3'-phosphoesterase domain.
       0.796
AGB01862.1
Sulfur transfer protein involved in thiamine biosynthesis; PFAM: ThiS family.
  
    0.647
AGB01215.1
PFAM: ThiC family; TIGRFAM: thiamine biosynthesis protein ThiC; manually curated.
  
  
 0.602
AGB02165.1
PFAM: ThiC family; TIGRFAM: thiamine biosynthesis protein ThiC.
  
  
 0.602
Your Current Organism:
Methanoregula formicica
NCBI taxonomy Id: 593750
Other names: M. formicica SMSP, Methanomicrobiales archaeon SMSP, Methanoregula formicica SMSP, Methanoregula formicica str. SMSP, Methanoregula formicica strain SMSP
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