Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB02024.1ACT domain-containing protein; PFAM: ACT domain. (227 aa)    
Predicted Functional Partners:
AGB02023.1
PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein.
       0.906
htpX
Zn-dependent protease with chaperone function; PFAM: Peptidase family M48; Belongs to the peptidase M48B family.
  
    0.879
AGB02022.1
Hypothetical protein; PFAM: Nucleotidyltransferase domain.
 
     0.876
alaS
alanine--tRNA ligase/alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
 
    0.801
AGB03663.1
PFAM: Uroporphyrinogen-III synthase HemD.
  
    0.800
AGB02693.1
PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain.
  
    0.686
AGB03876.1
PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain.
  
    0.686
mtd
Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
  
     0.643
AGB01200.1
Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V.
  
    0.568
AGB03544.1
PFAM: tRNA synthetases class I (W and Y); Belongs to the class-I aminoacyl-tRNA synthetase family.
  
    0.544
Your Current Organism:
Methanoregula formicica
NCBI taxonomy Id: 593750
Other names: M. formicica SMSP, Methanomicrobiales archaeon SMSP, Methanoregula formicica SMSP, Methanoregula formicica str. SMSP, Methanoregula formicica strain SMSP
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