Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB02028.1Parallel beta-helix repeat (two copies); PFAM: Protein kinase domain; Periplasmic copper-binding protein (NosD); TIGRFAM: parallel beta-helix repeat (two copies). (704 aa)    
Predicted Functional Partners:
AGB01540.1
PFAM: GTPase of unknown function.
   
 0.845
AGB03828.1
PFAM: Phosphoribulokinase / Uridine kinase family.
  
 0.826
AGB02027.1
FHA domain-containing protein; PFAM: FHA domain.
 
 
 
 0.782
AGB02328.1
PFAM: Calcineurin-like phosphoesterase.
   
 0.748
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
    
 0.747
AGB02103.1
Inorganic pyrophosphatase/exopolyphosphatase; PFAM: DHH family; DRTGG domain; DHHA2 domain; CBS domain.
  
 
 
 0.737
AGB03813.1
PFAM: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD.
 
 
 0.736
AGB03761.1
PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins.
  
 
 0.730
AGB03549.1
WD40 repeat-containing protein; PFAM: WD domain, G-beta repeat.
 
 0.716
AGB02767.1
Short-chain alcohol dehydrogenase; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 0.703
Your Current Organism:
Methanoregula formicica
NCBI taxonomy Id: 593750
Other names: M. formicica SMSP, Methanomicrobiales archaeon SMSP, Methanoregula formicica SMSP, Methanoregula formicica str. SMSP, Methanoregula formicica strain SMSP
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