Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB02053.1PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain. (261 aa)    
Predicted Functional Partners:
eif2b
Translation initiation factor aIF-2, beta subunit, putative; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family.
  
 0.997
AGB03848.1
PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; Initiation factor eIF2 gamma, C terminal; TIGRFAM: small GTP-binding protein domain; translation initiation factor 2 subunit gamma.
  
 0.994
rps3ae
PFAM: Ribosomal S3Ae family; Belongs to the eukaryotic ribosomal protein eS1 family.
  
 0.993
rps3
Ribosomal protein S3, eukaryotic/archaeal type; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
   
 0.992
AGB02054.1
PFAM: Nucleolar RNA-binding protein, Nop10p family; manually curated.
  
  
 0.991
rps6e
PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
  
 0.990
rps5
Ribosomal protein S5/S2; With S4 and S12 plays an important role in translational accuracy.
   
 0.990
rps19p
Ribosomal protein S19/S15; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
  
 0.990
rps10
Ribosomal protein S10/S20; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
 0.989
eif1a
Eukaryotic/archaeal initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
  
 0.987
Your Current Organism:
Methanoregula formicica
NCBI taxonomy Id: 593750
Other names: M. formicica SMSP, Methanomicrobiales archaeon SMSP, Methanoregula formicica SMSP, Methanoregula formicica str. SMSP, Methanoregula formicica strain SMSP
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