Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AGB02059.1Kef-type K+ transport system, predicted NAD-binding component; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family; TrkA-C domain; TIGRFAM: transporter, monovalent cation:proton antiporter-2 (CPA2) family. (672 aa)    
Predicted Functional Partners:
AGB01779.1
NhaP-type Na+(K+)/H+ antiporter; PFAM: Sodium/hydrogen exchanger family; TrkA-C domain.
  
  
 0.925
AGB03189.1
Alcohol dehydrogenase, class IV; PFAM: Iron-containing alcohol dehydrogenase.
  
  
 0.706
AGB03808.1
PFAM: Aldo/keto reductase family.
  
    0.681
AGB03831.1
Helicase family protein with metal-binding cysteine cluster; PFAM: Helicase conserved C-terminal domain; Domain of unknown function (DUF1998); DEAD/DEAH box helicase.
  
    0.676
AGB02303.1
Kef-type K+ transport system, predicted NAD-binding component; PFAM: TrkA-N domain; TrkA-C domain; Sodium/hydrogen exchanger family; TIGRFAM: transporter, monovalent cation:proton antiporter-2 (CPA2) family.
  
  
 0.658
AGB03730.1
Kef-type K+ transport system, membrane component; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family; TrkA-C domain.
  
  
 0.658
AGB02639.1
Hypothetical protein.
   
    0.609
AGB01534.1
Hypothetical protein.
   
    0.605
AGB02591.1
PFAM: CAAX amino terminal protease family.
  
  
 0.599
AGB02876.1
PFAM: CAAX amino terminal protease family.
  
  
 0.599
Your Current Organism:
Methanoregula formicica
NCBI taxonomy Id: 593750
Other names: M. formicica SMSP, Methanomicrobiales archaeon SMSP, Methanoregula formicica SMSP, Methanoregula formicica str. SMSP, Methanoregula formicica strain SMSP
Server load: low (16%) [HD]