Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB02987.1PFAM: FTR, proximal lobe; lobe; TIGRFAM: formylmethanofuran--tetrahydromethanopterin N-formyltransferase. (296 aa)    
Predicted Functional Partners:
mch
Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family.
 
 
 0.990
fae-hps
Formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the N-terminal section; belongs to the formaldehyde- activating enzyme family.
  
  
 0.978
AGB01696.1
PFAM: Amidohydrolase family; TIGRFAM: formylmethanofuran dehydrogenase subunit A.
 
 
 0.974
AGB01716.1
PFAM: Amidohydrolase family; TIGRFAM: formylmethanofuran dehydrogenase subunit A.
 
 
 0.974
AGB01745.1
PFAM: Amidohydrolase family; TIGRFAM: formylmethanofuran dehydrogenase subunit A.
 
 
 0.974
AGB01717.1
PFAM: Molybdopterin oxidoreductase; TIGRFAM: formylmethanofuran dehydrogenase subunit B.
 
 
 0.953
mtrA
N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family.
     
 0.949
AGB01695.1
PFAM: Molybdopterin oxidoreductase; TIGRFAM: formylmethanofuran dehydrogenase subunit B.
 
 
 0.948
AGB03613.1
PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit; TIGRFAM: N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit H.
     
 0.944
AGB01744.1
PFAM: Molybdopterin oxidoreductase; TIGRFAM: formylmethanofuran dehydrogenase subunit B.
 
 
 0.942
Your Current Organism:
Methanoregula formicica
NCBI taxonomy Id: 593750
Other names: M. formicica SMSP, Methanomicrobiales archaeon SMSP, Methanoregula formicica SMSP, Methanoregula formicica str. SMSP, Methanoregula formicica strain SMSP
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