Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB02992.1Heat shock protein; PFAM: META domain. (169 aa)    
Predicted Functional Partners:
purL
Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and [...]
 
     0.752
AGB02993.1
PFAM: Cache domain.
       0.557
AGB01578.1
ABC-type transport system, involved in lipoprotein release, permease component; PFAM: Predicted permease.
 
 
 
 0.534
AGB01550.1
ABC-type transport system, involved in lipoprotein release, permease component; PFAM: Predicted permease.
 
 
 
 0.532
AGB01145.1
Succinate dehydrogenase/fumarate reductase flavoprotein subunit; PFAM: domain; FAD binding domain.
   
 
 0.473
mfnA
Tyrosine decarboxylase MnfA; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily.
   
 
 0.472
AGB01179.1
ABC-type transport system, involved in lipoprotein release, permease component; PFAM: Predicted permease.
   
 
 0.470
AGB01897.1
ABC-type transport system, involved in lipoprotein release, permease component; PFAM: Predicted permease.
   
 
 0.470
AGB03211.1
ABC-type transport system, involved in lipoprotein release, permease component; PFAM: Predicted permease.
   
 
 0.470
AGB01178.1
ABC-type antimicrobial peptide transport system, ATPase component; PFAM: ABC transporter.
   
   0.458
Your Current Organism:
Methanoregula formicica
NCBI taxonomy Id: 593750
Other names: M. formicica SMSP, Methanomicrobiales archaeon SMSP, Methanoregula formicica SMSP, Methanoregula formicica str. SMSP, Methanoregula formicica strain SMSP
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