Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AGB03001.1Sep-tRNA:Cys-tRNA synthase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family. (393 aa)    
Predicted Functional Partners:
sepS
O-phosphoseryl-tRNA(Cys) synthetase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys).
  
 0.990
cysS
PFAM: tRNA synthetases class I (C) catalytic domain; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.921
AGB03468.1
Sep-tRNA:Cys-tRNA synthase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family.
  
  
 
0.902
AGB03000.1
Hypothetical protein.
       0.799
AGB02064.1
K+ transport system, NAD-binding component; PFAM: TrkA-N domain; TrkA-C domain.
   
    0.693
AGB01779.1
NhaP-type Na+(K+)/H+ antiporter; PFAM: Sodium/hydrogen exchanger family; TrkA-C domain.
   
    0.601
AGB03282.1
PFAM: Peptidyl-tRNA hydrolase PTH2; TIGRFAM: peptidyl-tRNA hydrolase.
  
  
  0.562
AGB01295.1
TIGRFAM: putative methanogenesis marker protein 3; Belongs to the UPF0288 family.
  
    0.519
AGB02998.1
PFAM: MatE; TIGRFAM: putative efflux protein, MATE family.
       0.491
AGB02999.1
Transcriptional regulator; PFAM: MarR family; manually curated.
       0.491
Your Current Organism:
Methanoregula formicica
NCBI taxonomy Id: 593750
Other names: M. formicica SMSP, Methanomicrobiales archaeon SMSP, Methanoregula formicica SMSP, Methanoregula formicica str. SMSP, Methanoregula formicica strain SMSP
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