| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB01786.1 | thiI | Metfor_0726 | Metfor_2004 | ABC-type cobalt transport system, permease component CbiQ; PFAM: Cobalt transport protein. | Thiazole biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.464 |
| AGB01786.1 | thiI-2 | Metfor_0726 | Metfor_2478 | ABC-type cobalt transport system, permease component CbiQ; PFAM: Cobalt transport protein. | Thiazole biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.442 |
| AGB01786.1 | truA | Metfor_0726 | Metfor_2897 | ABC-type cobalt transport system, permease component CbiQ; PFAM: Cobalt transport protein. | Pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. | 0.658 |
| AGB03017.1 | AGB03020.1 | Metfor_2003 | Metfor_2006 | Pyruvate formate lyase activating protein-like uncharacterized Fe-S protein; PFAM: Radical SAM superfamily. | Hypothetical protein. | 0.434 |
| AGB03017.1 | thiI | Metfor_2003 | Metfor_2004 | Pyruvate formate lyase activating protein-like uncharacterized Fe-S protein; PFAM: Radical SAM superfamily. | Thiazole biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.709 |
| AGB03019.1 | AGB03020.1 | Metfor_2005 | Metfor_2006 | PFAM: Uncharacterized protein conserved in archaea (DUF2150). | Hypothetical protein. | 0.877 |
| AGB03019.1 | thiI | Metfor_2005 | Metfor_2004 | PFAM: Uncharacterized protein conserved in archaea (DUF2150). | Thiazole biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.438 |
| AGB03020.1 | AGB03017.1 | Metfor_2006 | Metfor_2003 | Hypothetical protein. | Pyruvate formate lyase activating protein-like uncharacterized Fe-S protein; PFAM: Radical SAM superfamily. | 0.434 |
| AGB03020.1 | AGB03019.1 | Metfor_2006 | Metfor_2005 | Hypothetical protein. | PFAM: Uncharacterized protein conserved in archaea (DUF2150). | 0.877 |
| AGB03020.1 | thiI | Metfor_2006 | Metfor_2004 | Hypothetical protein. | Thiazole biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.504 |
| AGB03674.1 | iscS | Metfor_2686 | Metfor_2456 | MiaB-like tRNA modifying enzyme; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: MiaB-like tRNA modifying enzyme, archaeal-type; radical SAM methylthiotransferase, MiaB/RimO family. | Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.547 |
| AGB03674.1 | thiI | Metfor_2686 | Metfor_2004 | MiaB-like tRNA modifying enzyme; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: MiaB-like tRNA modifying enzyme, archaeal-type; radical SAM methylthiotransferase, MiaB/RimO family. | Thiazole biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.544 |
| AGB03674.1 | thiI-2 | Metfor_2686 | Metfor_2478 | MiaB-like tRNA modifying enzyme; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: MiaB-like tRNA modifying enzyme, archaeal-type; radical SAM methylthiotransferase, MiaB/RimO family. | Thiazole biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.544 |
| AGB03674.1 | truA | Metfor_2686 | Metfor_2897 | MiaB-like tRNA modifying enzyme; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: MiaB-like tRNA modifying enzyme, archaeal-type; radical SAM methylthiotransferase, MiaB/RimO family. | Pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. | 0.543 |
| iscS | AGB03674.1 | Metfor_2456 | Metfor_2686 | Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | MiaB-like tRNA modifying enzyme; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: MiaB-like tRNA modifying enzyme, archaeal-type; radical SAM methylthiotransferase, MiaB/RimO family. | 0.547 |
| iscS | thiI | Metfor_2456 | Metfor_2004 | Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | Thiazole biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.976 |
| iscS | thiI-2 | Metfor_2456 | Metfor_2478 | Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | Thiazole biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.976 |
| iscS | truA | Metfor_2456 | Metfor_2897 | Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | Pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. | 0.407 |
| sepS | thiI | Metfor_2843 | Metfor_2004 | O-phosphoseryl-tRNA(Cys) synthetase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys). | Thiazole biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.463 |
| sepS | truA | Metfor_2843 | Metfor_2897 | O-phosphoseryl-tRNA(Cys) synthetase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys). | Pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. | 0.445 |
STRING v12.5 is now available!
