STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGB03030.1PFAM: Uncharacterized conserved protein (DUF2081); Protein of unknown function DUF262. (613 aa)    
Predicted Functional Partners:
cas1
CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
     0.678
AGB03032.1
Hypothetical protein; Manually curated.
       0.598
AGB01881.1
Putative transcriptional regulator with HTH domain; PFAM: Bacterial regulatory protein, arsR family; Divergent AAA domain.
 
    0.511
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
       0.507
AGB03028.1
Putative transcriptional regulator with HTH domain; PFAM: Divergent AAA domain.
 
    0.499
AGB02763.1
Putative transcriptional regulator with HTH domain; PFAM: Divergent AAA domain.
 
    0.497
AGB02760.1
Type I restriction-modification system methyltransferase subunit; PFAM: Type I restriction enzyme R protein N terminus (HSDR_N); N-6 DNA Methylase; Eco57I restriction endonuclease.
  
    0.466
AGB03427.1
Adenine-specific DNA methylase containing a Zn-ribbon; PFAM: Protein of unknown function (DUF1156).
 
     0.423
AGB03029.1
Hypothetical protein.
       0.414
AGB03426.1
DNA/RNA helicase, superfamily II, SNF2 family; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain.
 
     0.413
Your Current Organism:
Methanoregula formicica
NCBI taxonomy Id: 593750
Other names: M. formicica SMSP, Methanomicrobiales archaeon SMSP, Methanoregula formicica SMSP, Methanoregula formicica str. SMSP, Methanoregula formicica strain SMSP
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.