close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rbcLRibulose bisphosphate carboxylase, type III; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. (430 aa)    
Predicted Functional Partners:
AGB02184.1
Isoleucine patch superfamily enzyme, carbonic anhydrase/acetyltransferase.
   
 
 0.908
AGB01811.1
Sucrose-phosphate phosphatase-like hydrolase, Archaeal; Catalyzes the dephosphorylation of 2-phosphoglycolate.
    
 0.903
AGB03828.1
PFAM: Phosphoribulokinase / Uridine kinase family.
 
   
 0.865
AGB01298.1
PFAM: Initiation factor 2 subunit family; TIGRFAM: ribose-1,5-bisphosphate isomerase, e2b2 family; eIF-2B alpha/beta/delta-related uncharacterized proteins; Belongs to the eIF-2B alpha/beta/delta subunits family.
 
  
 0.855
fbp
Fructose-1,6-bisphosphatase; PFAM: Fructose-1-6-bisphosphatase.
 
  
 0.806
AGB02374.1
Ribulose-5-phosphate 4-epimerase-like epimerase or aldolase; PFAM: Class II Aldolase and Adducin N-terminal domain.
  
  
 0.781
AGB02182.1
S-methyl-5-thioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
  
  
 0.723
AGB03469.1
OAH/OAS sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase.
  
  
 0.677
AGB03656.1
AMP phosphorylase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
 
   
 0.600
AGB02647.1
PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: YD repeat (two copies).
  
  
 0.578
Your Current Organism:
Methanoregula formicica
NCBI taxonomy Id: 593750
Other names: M. formicica SMSP, Methanomicrobiales archaeon SMSP, Methanoregula formicica SMSP, Methanoregula formicica str. SMSP, Methanoregula formicica strain SMSP
Server load: low (20%) [HD]