Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB03452.1Fe-S oxidoreductase; PFAM: Cysteine-rich domain; manually curated. (388 aa)    
Predicted Functional Partners:
AGB03451.1
Hypothetical protein.
       0.773
gap
Glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II.
  
  
 0.540
AGB03593.1
TIGRFAM: CoB--CoM heterodisulfide reductase, subunit C.
 
 
 
 0.489
AGB02724.1
PFAM: L-lactate permease.
  
  
 0.457
AGB03594.1
PFAM: Cysteine-rich domain; TIGRFAM: CoB--CoM heterodisulfide reductase, subunit B.
 
 
 
 0.448
AGB03127.1
Putative Fe-S oxidoreductase; PFAM: Radical SAM superfamily.
 
     0.442
AGB03595.1
Polyferredoxin, heterodixulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
 
   
 0.438
AGB02183.1
Pyridine nucleotide-disulfide oxidoreductase; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
 
   
 0.416
AGB03596.1
PFAM: Methyl-viologen-reducing hydrogenase, delta subunit.
 
   
 0.416
Your Current Organism:
Methanoregula formicica
NCBI taxonomy Id: 593750
Other names: M. formicica SMSP, Methanomicrobiales archaeon SMSP, Methanoregula formicica SMSP, Methanoregula formicica str. SMSP, Methanoregula formicica strain SMSP
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