Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB03494.1Coenzyme F390 synthetase; PFAM: AMP-binding enzyme. (429 aa)    
Predicted Functional Partners:
AGB03495.1
Coenzyme F390 synthetase; PFAM: AMP-binding enzyme.
 
  
 
0.990
AGB03496.1
ACT domain-containing protein; PFAM: ACT domain.
 
   0.961
AGB02735.1
Hypothetical protein; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1.
 
 
 0.938
AGB01467.1
PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.
  
 
 0.706
AGB02694.1
PFAM: Aldehyde dehydrogenase family.
  
 
 0.706
AGB03461.1
Serine O-acetyltransferase; PFAM: Domain of unknown function DUF59; TIGRFAM: serine O-acetyltransferase.
     
 0.687
cas1-3
CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
       0.527
AGB02728.1
ABC-type branched-chain amino acid transport systems, ATPase component; PFAM: ABC transporter.
 
  
 0.458
AGB01759.1
Hypothetical protein; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1.
 
  
 0.401
Your Current Organism:
Methanoregula formicica
NCBI taxonomy Id: 593750
Other names: M. formicica SMSP, Methanomicrobiales archaeon SMSP, Methanoregula formicica SMSP, Methanoregula formicica str. SMSP, Methanoregula formicica strain SMSP
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