STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGB03539.1PFAM: 8-oxoguanine DNA glycosylase, N-terminal domain; HhH-GPD superfamily base excision DNA repair protein; TIGRFAM: 8-oxoguanine DNA-glycosylase (ogg). (282 aa)    
Predicted Functional Partners:
dbh
nucleotidyltransferase/DNA polymerase involved in DNA repair; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis.
  
 
 0.791
AGB03226.1
PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Helix-hairpin-helix motif.
    
   0.704
pyrB
PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase.
     0.670
nfo
Apurinic endonuclease APN1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
   
 
 0.601
AGB03426.1
DNA/RNA helicase, superfamily II, SNF2 family; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain.
  
 
 0.526
AGB03538.1
Hypothetical protein.
       0.525
AGB03164.1
PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase.
  
  
 0.486
AGB03171.1
DNA polymerase elongation subunit (family B); PFAM: DNA polymerase family B; DNA polymerase family B, exonuclease domain.
   
 
 0.480
AGB03251.1
DNA polymerase elongation subunit (family B); PFAM: DNA polymerase family B.
   
 
 0.480
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
  
 
 0.464
Your Current Organism:
Methanoregula formicica
NCBI taxonomy Id: 593750
Other names: M. formicica SMSP, Methanomicrobiales archaeon SMSP, Methanoregula formicica SMSP, Methanoregula formicica str. SMSP, Methanoregula formicica strain SMSP
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.