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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGB03661.1rRNA biogenesis protein; PFAM: Putative snoRNA binding domain. (286 aa)    
Predicted Functional Partners:
rpl7ae
50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
 
 0.999
flpA
Fibrillarin-like rRNA methylase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
 
 
 0.998
truB
rRNA pseudouridine synthase, putative; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
 
 
 0.998
rps6e
PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
  
 0.996
rps4
Ribosomal protein S4/S9; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
 0.994
rps11
Archaeal ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
  
 0.994
rps3ae
PFAM: Ribosomal S3Ae family; Belongs to the eukaryotic ribosomal protein eS1 family.
 
  0.991
AGB01265.1
PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein.
  
 
 0.987
AGB01807.1
PFAM: Nucleolar GTP-binding protein 1 (NOG1); TIGRFAM: small GTP-binding protein domain.
  
 
 0.986
rpl18
Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
 
 
 0.983
Your Current Organism:
Methanoregula formicica
NCBI taxonomy Id: 593750
Other names: M. formicica SMSP, Methanomicrobiales archaeon SMSP, Methanoregula formicica SMSP, Methanoregula formicica str. SMSP, Methanoregula formicica strain SMSP
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