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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
htpXZn-dependent protease with chaperone function; PFAM: Peptidase family M48; Belongs to the peptidase M48B family. (294 aa)    
Predicted Functional Partners:
AGB02024.1
ACT domain-containing protein; PFAM: ACT domain.
  
    0.798
AGB02384.1
Putative kinase, sugar kinase superfamily; PFAM: GHMP kinases N terminal domain.
  
    0.790
alaS
alanine--tRNA ligase/alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
    0.761
AGB01805.1
PFAM: ATPase family associated with various cellular activities (AAA).
  
  
 0.603
AGB02890.1
PFAM: ATPase family associated with various cellular activities (AAA).
  
  
 0.603
AGB02266.1
PFAM: Conserved region in glutamate synthase; Belongs to the glutamate synthase family.
     
 0.592
AGB01145.1
Succinate dehydrogenase/fumarate reductase flavoprotein subunit; PFAM: domain; FAD binding domain.
  
  
 0.589
AGB03858.1
PFAM: Domain of unknown function (DUF1917).
       0.589
AGB02557.1
Putative ATPase, Rnase L inhibitor (RLI) like protein; PFAM: ABC transporter; 4Fe-4S binding domain; Possible metal-binding domain in RNase L inhibitor, RLI.
  
    0.587
rpl4
50S ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
  
 
 0.556
Your Current Organism:
Methanoregula formicica
NCBI taxonomy Id: 593750
Other names: M. formicica SMSP, Methanomicrobiales archaeon SMSP, Methanoregula formicica SMSP, Methanoregula formicica str. SMSP, Methanoregula formicica strain SMSP
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.