STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panCPantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (301 aa)    
Predicted Functional Partners:
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
 
 0.999
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
  
 0.999
AEI10887.1
PFAM: Putative oxidoreductase/dehydrogenase, Rossmann-like domain; Domain of unknown function DUF2520; KEGG: putative oxidoreductase/dehydrogenase, Rossmann-like domain protein.
   
 0.978
coaA
TIGRFAM: pantothenate kinase; KEGG: pantothenate kinase.
     
 0.930
cmk
KEGG: cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; shikimate kinase.
      0.907
AEI12646.1
PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase.
  
 
 0.905
AEI12639.1
PFAM: aminotransferase class-III; KEGG: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.903
AEI12282.1
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
 
 0.892
AEI10890.1
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
 
   
 0.887
AEI10883.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
   
 0.882
Your Current Organism:
Cellulomonas gilvus
NCBI taxonomy Id: 593907
Other names: C. gilvus ATCC 13127, Cellulomonas gilvus ATCC 13127, Cellulomonas gilvus str. ATCC 13127, Cellulomonas gilvus strain ATCC 13127, Cellvibrio gilvus ATCC 13127
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