STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (200 aa)    
Predicted Functional Partners:
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.983
AEI12737.1
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
 
 
 0.973
AEI10891.1
TIGRFAM: nicotinate-nucleotide pyrophosphorylase; KEGG: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family.
    
 0.966
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
 
 0.936
AEI12554.1
PFAM: CinA domain protein; KEGG: CinA domain protein; Belongs to the CinA family.
  
 
 0.935
AEI13282.1
PFAM: Silent information regulator protein Sir2; KEGG: silent information regulator protein Sir2.
   
 0.920
AEI12858.1
KEGG: mbt:JTY_0218 putative transcriptional regulatory protein.
     
 0.912
AEI11149.1
KEGG: NAD(P) transhydrogenase, alpha subunit; TIGRFAM: NAD(P) transhydrogenase, alpha subunit; PFAM: alanine dehydrogenase/PNT domain protein.
     
 0.905
AEI11494.1
PFAM: NUDIX hydrolase; Zinc ribbon NADH pyrophosphatase; NADH pyrophosphatase-like; KEGG: NAD(+) diphosphatase.
     
 0.904
AEI11150.1
NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.901
Your Current Organism:
Cellulomonas gilvus
NCBI taxonomy Id: 593907
Other names: C. gilvus ATCC 13127, Cellulomonas gilvus ATCC 13127, Cellulomonas gilvus str. ATCC 13127, Cellulomonas gilvus strain ATCC 13127, Cellvibrio gilvus ATCC 13127
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