STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recCExodeoxyribonuclease V, gamma subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...] (1173 aa)    
Predicted Functional Partners:
recB
Exodeoxyribonuclease V; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzy [...]
 
 
 0.997
recD
Exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...]
 
 0.993
AEI11045.1
TrwC relaxase; KEGG: mlu:Mlut_00370 conjugative relaxase domain protein, TrwC/TraI family; PFAM: TrwC relaxase; SMART: AAA ATPase.
  
 
 0.697
AEI12805.1
PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; KEGG: ATP dependent DNA ligase.
      
 0.612
AEI12173.1
KEGG: hypothetical protein.
  
     0.573
AEI12763.1
KEGG: ach:Achl_1142 23S rRNA (uracil-5-)-methyltransferase RumB; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumB; PFAM: (Uracil-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
       0.561
AEI13206.1
KEGG: cwo:Cwoe_0405 hypothetical protein.
  
     0.544
AEI10934.1
KEGG: nca:Noca_0373 hypothetical protein.
  
     0.505
AEI11679.1
KEGG: DEAD/DEAH box helicase domain protein; PFAM: DEAD/DEAH box helicase domain protein; nucleic acid binding OB-fold tRNA/helicase-type; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein.
      
 0.479
AEI10935.1
KEGG: nca:Noca_0373 hypothetical protein.
  
     0.472
Your Current Organism:
Cellulomonas gilvus
NCBI taxonomy Id: 593907
Other names: C. gilvus ATCC 13127, Cellulomonas gilvus ATCC 13127, Cellulomonas gilvus str. ATCC 13127, Cellulomonas gilvus strain ATCC 13127, Cellvibrio gilvus ATCC 13127
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.