DHX8 protein (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DHX8

Uncharacterized protein. (1239 aa)

Predicted Functional Partners:

CDC40

0.996

SLU7

0.996

AQR

0.976

CRNKL1

0.975

SRRM1

0.973

SYF2

0.967

IMP3

0.949

BUD31

0.947

DDX49

0.945

UTP3

0.943

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQR	BUD31	ENSMLUP00000005703	ENSMLUP00000009985	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	BUD31 homolog.	0.999
AQR	CDC40	ENSMLUP00000005703	ENSMLUP00000001653	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Cell division cycle 40.	0.997
AQR	CRNKL1	ENSMLUP00000005703	ENSMLUP00000015058	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Crooked neck pre-mRNA splicing factor 1.	0.999
AQR	DDX49	ENSMLUP00000005703	ENSMLUP00000011080	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	DEAD-box helicase 49; Belongs to the DEAD box helicase family.	0.454
AQR	DHX8	ENSMLUP00000005703	ENSMLUP00000000085	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Uncharacterized protein.	0.976
AQR	SLU7	ENSMLUP00000005703	ENSMLUP00000002811	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	SLU7 homolog, splicing factor.	0.958
AQR	SRRM1	ENSMLUP00000005703	ENSMLUP00000005712	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Serine and arginine repetitive matrix 1.	0.808
AQR	SYF2	ENSMLUP00000005703	ENSMLUP00000001715	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	SYF2 pre-mRNA splicing factor.	0.976
BUD31	AQR	ENSMLUP00000009985	ENSMLUP00000005703	BUD31 homolog.	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	0.999
BUD31	CDC40	ENSMLUP00000009985	ENSMLUP00000001653	BUD31 homolog.	Cell division cycle 40.	0.998
BUD31	CRNKL1	ENSMLUP00000009985	ENSMLUP00000015058	BUD31 homolog.	Crooked neck pre-mRNA splicing factor 1.	0.999
BUD31	DDX49	ENSMLUP00000009985	ENSMLUP00000011080	BUD31 homolog.	DEAD-box helicase 49; Belongs to the DEAD box helicase family.	0.453
BUD31	DHX8	ENSMLUP00000009985	ENSMLUP00000000085	BUD31 homolog.	Uncharacterized protein.	0.947
BUD31	SLU7	ENSMLUP00000009985	ENSMLUP00000002811	BUD31 homolog.	SLU7 homolog, splicing factor.	0.998
BUD31	SRRM1	ENSMLUP00000009985	ENSMLUP00000005712	BUD31 homolog.	Serine and arginine repetitive matrix 1.	0.777
BUD31	SYF2	ENSMLUP00000009985	ENSMLUP00000001715	BUD31 homolog.	SYF2 pre-mRNA splicing factor.	0.998
CDC40	AQR	ENSMLUP00000001653	ENSMLUP00000005703	Cell division cycle 40.	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	0.997
CDC40	BUD31	ENSMLUP00000001653	ENSMLUP00000009985	Cell division cycle 40.	BUD31 homolog.	0.998
CDC40	CRNKL1	ENSMLUP00000001653	ENSMLUP00000015058	Cell division cycle 40.	Crooked neck pre-mRNA splicing factor 1.	0.998
CDC40	DDX49	ENSMLUP00000001653	ENSMLUP00000011080	Cell division cycle 40.	DEAD-box helicase 49; Belongs to the DEAD box helicase family.	0.592