DDRGK1 protein (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DDRGK1

DDRGK domain containing 1. (310 aa)

Predicted Functional Partners:

CDK5RAP3

0.983

UFL1

0.977

UFC1

0.857

LOC102419772

0.819

UFSP2

0.708

SRP68

0.703

TMED2

0.699

SRPRA

0.684

SPRY3

0.677

UBA5

0.676

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDK5RAP3	DDRGK1	ENSMLUP00000004579	ENSMLUP00000000321	CDK5 regulatory subunit associated protein 3.	DDRGK domain containing 1.	0.983
CDK5RAP3	LOC102419772	ENSMLUP00000004579	ENSMLUP00000021063	CDK5 regulatory subunit associated protein 3.	Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached to substrate proteins as a monomer or a lysine-linked polymer in a post- translational process called ufmylation. Ufmylation on lysine residues of proteins may play a crucial role in a number of cellular processes.	0.603
CDK5RAP3	UBA5	ENSMLUP00000004579	ENSMLUP00000000754	CDK5 regulatory subunit associated protein 3.	Ubiquitin like modifier activating enzyme 5.	0.588
CDK5RAP3	UFC1	ENSMLUP00000004579	ENSMLUP00000004131	CDK5 regulatory subunit associated protein 3.	Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.	0.718
CDK5RAP3	UFL1	ENSMLUP00000004579	ENSMLUP00000011117	CDK5 regulatory subunit associated protein 3.	UFM1 specific ligase 1.	0.977
CDK5RAP3	UFSP2	ENSMLUP00000004579	ENSMLUP00000005542	CDK5 regulatory subunit associated protein 3.	UFM1 specific peptidase 2.	0.740
DDRGK1	CDK5RAP3	ENSMLUP00000000321	ENSMLUP00000004579	DDRGK domain containing 1.	CDK5 regulatory subunit associated protein 3.	0.983
DDRGK1	LOC102419772	ENSMLUP00000000321	ENSMLUP00000021063	DDRGK domain containing 1.	Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached to substrate proteins as a monomer or a lysine-linked polymer in a post- translational process called ufmylation. Ufmylation on lysine residues of proteins may play a crucial role in a number of cellular processes.	0.819
DDRGK1	SPRY3	ENSMLUP00000000321	ENSMLUP00000019765	DDRGK domain containing 1.	Sprouty RTK signaling antagonist 3.	0.677
DDRGK1	SRP68	ENSMLUP00000000321	ENSMLUP00000001129	DDRGK domain containing 1.	Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family.	0.703
DDRGK1	SRPRA	ENSMLUP00000000321	ENSMLUP00000015806	DDRGK domain containing 1.	SRP receptor subunit alpha.	0.684
DDRGK1	TMED2	ENSMLUP00000000321	ENSMLUP00000001156	DDRGK domain containing 1.	Transmembrane p24 trafficking protein 2.	0.699
DDRGK1	UBA5	ENSMLUP00000000321	ENSMLUP00000000754	DDRGK domain containing 1.	Ubiquitin like modifier activating enzyme 5.	0.676
DDRGK1	UFC1	ENSMLUP00000000321	ENSMLUP00000004131	DDRGK domain containing 1.	Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.	0.857
DDRGK1	UFL1	ENSMLUP00000000321	ENSMLUP00000011117	DDRGK domain containing 1.	UFM1 specific ligase 1.	0.977
DDRGK1	UFSP2	ENSMLUP00000000321	ENSMLUP00000005542	DDRGK domain containing 1.	UFM1 specific peptidase 2.	0.708
LOC102419772	CDK5RAP3	ENSMLUP00000021063	ENSMLUP00000004579	Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached to substrate proteins as a monomer or a lysine-linked polymer in a post- translational process called ufmylation. Ufmylation on lysine residues of proteins may play a crucial role in a number of cellular processes.	CDK5 regulatory subunit associated protein 3.	0.603
LOC102419772	DDRGK1	ENSMLUP00000021063	ENSMLUP00000000321	Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached to substrate proteins as a monomer or a lysine-linked polymer in a post- translational process called ufmylation. Ufmylation on lysine residues of proteins may play a crucial role in a number of cellular processes.	DDRGK domain containing 1.	0.819
LOC102419772	SRP68	ENSMLUP00000021063	ENSMLUP00000001129	Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached to substrate proteins as a monomer or a lysine-linked polymer in a post- translational process called ufmylation. Ufmylation on lysine residues of proteins may play a crucial role in a number of cellular processes.	Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family.	0.475
LOC102419772	TMED2	ENSMLUP00000021063	ENSMLUP00000001156	Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached to substrate proteins as a monomer or a lysine-linked polymer in a post- translational process called ufmylation. Ufmylation on lysine residues of proteins may play a crucial role in a number of cellular processes.	Transmembrane p24 trafficking protein 2.	0.498