Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HEG1Heart development protein with EGF like domains 1. (1279 aa)    
Predicted Functional Partners:
KRIT1
Uncharacterized protein.
    
 0.995
G1PUQ4_MYOLU
Uncharacterized protein.
    
 0.834
G1Q8Q7_MYOLU
Uncharacterized protein.
    
 0.825
MUC1
SEA domain-containing protein.
   
 0.801
MUC20
Uncharacterized protein.
     
 0.795
MUC15
Mucin 15, cell surface associated.
     
 0.779
G1Q0P9_MYOLU
SEA domain-containing protein.
   
 
 0.775
GALNT14
Polypeptide N-acetylgalactosaminyltransferase.
    
 0.742
RPA1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 
 0.724
WDFY3
WD repeat and FYVE domain containing 3.
    
 
 0.702
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
Server load: low (16%) [HD]