STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPR183G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (361 aa)    
Predicted Functional Partners:
GPR18
G protein-coupled receptor 18; Belongs to the G-protein coupled receptor 1 family.
   
 
0.766
HSD3B7
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; Belongs to the 3-beta-HSD family.
      
 0.737
CH25H
Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.
      
 0.708
CNR2
Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.680
MTNR1B
Melatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family.
   
 
0.670
CNR1
Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...]
   
 
 0.663
OXGR1
Oxoglutarate receptor 1.
     
0.643
TAGAP
T cell activation RhoGTPase activating protein.
   
  
 0.641
GPR50
G protein-coupled receptor 50; Belongs to the G-protein coupled receptor 1 family.
   
 
0.622
GNAI2
G protein subunit alpha i2.
    
 
 0.618
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
Server load: low (16%) [HD]