| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CH25H | GPR183 | ENSMLUP00000022390 | ENSMLUP00000001139 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. | 0.708 |
| CH25H | HSD3B7 | ENSMLUP00000022390 | ENSMLUP00000004297 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; Belongs to the 3-beta-HSD family. | 0.992 |
| CNR1 | CNR2 | ENSMLUP00000013631 | ENSMLUP00000017112 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | 0.912 |
| CNR1 | GNAI2 | ENSMLUP00000013631 | ENSMLUP00000002148 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | G protein subunit alpha i2. | 0.930 |
| CNR1 | GPR18 | ENSMLUP00000013631 | ENSMLUP00000015510 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | G protein-coupled receptor 18; Belongs to the G-protein coupled receptor 1 family. | 0.787 |
| CNR1 | GPR183 | ENSMLUP00000013631 | ENSMLUP00000001139 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. | 0.663 |
| CNR1 | GPR50 | ENSMLUP00000013631 | ENSMLUP00000011824 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | G protein-coupled receptor 50; Belongs to the G-protein coupled receptor 1 family. | 0.569 |
| CNR1 | MTNR1B | ENSMLUP00000013631 | ENSMLUP00000010580 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Melatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family. | 0.651 |
| CNR1 | OXGR1 | ENSMLUP00000013631 | ENSMLUP00000012577 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Oxoglutarate receptor 1. | 0.599 |
| CNR2 | CNR1 | ENSMLUP00000017112 | ENSMLUP00000013631 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | 0.912 |
| CNR2 | GNAI2 | ENSMLUP00000017112 | ENSMLUP00000002148 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | G protein subunit alpha i2. | 0.809 |
| CNR2 | GPR18 | ENSMLUP00000017112 | ENSMLUP00000015510 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | G protein-coupled receptor 18; Belongs to the G-protein coupled receptor 1 family. | 0.794 |
| CNR2 | GPR183 | ENSMLUP00000017112 | ENSMLUP00000001139 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. | 0.680 |
| CNR2 | GPR50 | ENSMLUP00000017112 | ENSMLUP00000011824 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | G protein-coupled receptor 50; Belongs to the G-protein coupled receptor 1 family. | 0.569 |
| CNR2 | MTNR1B | ENSMLUP00000017112 | ENSMLUP00000010580 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | Melatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family. | 0.671 |
| CNR2 | OXGR1 | ENSMLUP00000017112 | ENSMLUP00000012577 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | Oxoglutarate receptor 1. | 0.599 |
| GNAI2 | CNR1 | ENSMLUP00000002148 | ENSMLUP00000013631 | G protein subunit alpha i2. | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | 0.930 |
| GNAI2 | CNR2 | ENSMLUP00000002148 | ENSMLUP00000017112 | G protein subunit alpha i2. | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | 0.809 |
| GNAI2 | GPR183 | ENSMLUP00000002148 | ENSMLUP00000001139 | G protein subunit alpha i2. | G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. | 0.618 |
| GNAI2 | GPR50 | ENSMLUP00000002148 | ENSMLUP00000011824 | G protein subunit alpha i2. | G protein-coupled receptor 50; Belongs to the G-protein coupled receptor 1 family. | 0.709 |