CASQ1 protein (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

CASQ1

Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (401 aa)

Predicted Functional Partners:

TRDN

0.995

RYR1

0.969

RYR2

0.965

RYR3

0.952

G1QAK2_MYOLU

0.927

G1QEW7_MYOLU

0.927

LOC102420101

0.901

MYOZ1

0.864

MYL1

0.848

SRL

0.790

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASQ1	G1QAK2_MYOLU	ENSMLUP00000001162	ENSMLUP00000020735	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Uncharacterized protein.	0.927
CASQ1	G1QEW7_MYOLU	ENSMLUP00000001162	ENSMLUP00000022250	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Uncharacterized protein.	0.927
CASQ1	LOC102420101	ENSMLUP00000001162	ENSMLUP00000014559	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.901
CASQ1	MYL1	ENSMLUP00000001162	ENSMLUP00000002399	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Myosin light chain 1.	0.848
CASQ1	MYOZ1	ENSMLUP00000001162	ENSMLUP00000011584	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Myozenin 1.	0.864
CASQ1	RYR1	ENSMLUP00000001162	ENSMLUP00000009236	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Ryanodine receptor 1.	0.969
CASQ1	RYR2	ENSMLUP00000001162	ENSMLUP00000005869	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Ryanodine receptor 2.	0.965
CASQ1	RYR3	ENSMLUP00000001162	ENSMLUP00000004153	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Ryanodine receptor 3.	0.952
CASQ1	SRL	ENSMLUP00000001162	ENSMLUP00000020004	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Sarcalumenin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.790
CASQ1	TRDN	ENSMLUP00000001162	ENSMLUP00000000124	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Triadin.	0.995
G1QAK2_MYOLU	CASQ1	ENSMLUP00000020735	ENSMLUP00000001162	Uncharacterized protein.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.927
G1QAK2_MYOLU	G1QEW7_MYOLU	ENSMLUP00000020735	ENSMLUP00000022250	Uncharacterized protein.	Uncharacterized protein.	0.900
G1QAK2_MYOLU	LOC102420101	ENSMLUP00000020735	ENSMLUP00000014559	Uncharacterized protein.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.927
G1QAK2_MYOLU	RYR1	ENSMLUP00000020735	ENSMLUP00000009236	Uncharacterized protein.	Ryanodine receptor 1.	0.874
G1QAK2_MYOLU	RYR2	ENSMLUP00000020735	ENSMLUP00000005869	Uncharacterized protein.	Ryanodine receptor 2.	0.874
G1QAK2_MYOLU	RYR3	ENSMLUP00000020735	ENSMLUP00000004153	Uncharacterized protein.	Ryanodine receptor 3.	0.874
G1QAK2_MYOLU	TRDN	ENSMLUP00000020735	ENSMLUP00000000124	Uncharacterized protein.	Triadin.	0.961
G1QEW7_MYOLU	CASQ1	ENSMLUP00000022250	ENSMLUP00000001162	Uncharacterized protein.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.927
G1QEW7_MYOLU	G1QAK2_MYOLU	ENSMLUP00000022250	ENSMLUP00000020735	Uncharacterized protein.	Uncharacterized protein.	0.900
G1QEW7_MYOLU	LOC102420101	ENSMLUP00000022250	ENSMLUP00000014559	Uncharacterized protein.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.927