Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ISCA1Iron-sulfur cluster assembly 1. (175 aa)    
Predicted Functional Partners:
LOC102427324
Fe-S_biosyn domain-containing protein.
  
0.994
ISCA2
Fe-S_biosyn domain-containing protein.
  
0.994
ISCU
Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
  
 
 0.979
NFU1
NFU1 iron-sulfur cluster scaffold.
  
 
 0.962
NFS1
Aminotran_5 domain-containing protein.
  
 
 0.961
SCLY
Selenocysteine lyase.
  
 
 0.922
IBA57
Iron-sulfur cluster assembly factor IBA57.
  
 
 0.899
FXN
Frataxin.
   
 
 0.882
FDX2
2Fe-2S ferredoxin-type domain-containing protein.
  
 0.869
FDX1
Ferredoxin 1.
  
 0.869
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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