STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G1NVG4_MYOLUSerine protease; Belongs to the peptidase S1B family. (733 aa)    
Predicted Functional Partners:
DFFB
DFF40 domain-containing protein.
    
   0.645
RPL3
Ribosomal protein L3; Belongs to the universal ribosomal protein uL3 family.
    
   0.621
BRCA1
Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]
   
 
 0.572
RAE1
Ribonucleic acid export 1.
   
 
  0.561
VPS39
VPS39 subunit of HOPS complex.
      
 0.555
TPR
Translocated promoter region, nuclear basket protein.
     
 0.535
FBXW7
F-box and WD repeat domain containing 7.
      
 0.531
SEH1L
SEH1 like nucleoporin; Belongs to the WD repeat SEC13 family.
     
  0.508
NUP42
Nucleoporin 42.
     
 0.507
OSTF1
Osteoclast stimulating factor 1.
      
 0.504
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.