SNX17 protein (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

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Co-occurrence

Co-expression

Experiments

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[Homology]

Score

SNX17

Sorting nexin 17. (470 aa)

Predicted Functional Partners:

VPS35L

0.953

VPS29

0.930

VPS35

0.928

VPS26C

0.925

ENSMLUP00000018188

0.925

SELP

0.862

SELE

0.862

SNX6

0.829

LRP8

0.824

VPS26A

0.795

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMLUP00000018188	SNX17	ENSMLUP00000018188	ENSMLUP00000001265	annotation not available	Sorting nexin 17.	0.925
ENSMLUP00000018188	VPS29	ENSMLUP00000018188	ENSMLUP00000014149	annotation not available	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.969
ENSMLUP00000018188	VPS35	ENSMLUP00000018188	ENSMLUP00000012965	annotation not available	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.601
ENSMLUP00000018188	VPS35L	ENSMLUP00000018188	ENSMLUP00000002678	annotation not available	VPS35 endosomal protein sorting factor like.	0.967
LRP8	SNX17	ENSMLUP00000022666	ENSMLUP00000001265	LDL receptor related protein 8.	Sorting nexin 17.	0.824
SELE	SNX17	ENSMLUP00000007837	ENSMLUP00000001265	Selectin E.	Sorting nexin 17.	0.862
SELP	SNX17	ENSMLUP00000007789	ENSMLUP00000001265	Selectin P.	Sorting nexin 17.	0.862
SNX17	ENSMLUP00000018188	ENSMLUP00000001265	ENSMLUP00000018188	Sorting nexin 17.	annotation not available	0.925
SNX17	LRP8	ENSMLUP00000001265	ENSMLUP00000022666	Sorting nexin 17.	LDL receptor related protein 8.	0.824
SNX17	SELE	ENSMLUP00000001265	ENSMLUP00000007837	Sorting nexin 17.	Selectin E.	0.862
SNX17	SELP	ENSMLUP00000001265	ENSMLUP00000007789	Sorting nexin 17.	Selectin P.	0.862
SNX17	SNX6	ENSMLUP00000001265	ENSMLUP00000006437	Sorting nexin 17.	Sorting nexin; Involved in several stages of intracellular trafficking.	0.829
SNX17	VPS26A	ENSMLUP00000001265	ENSMLUP00000011518	Sorting nexin 17.	VPS26, retromer complex component A.	0.795
SNX17	VPS26C	ENSMLUP00000001265	ENSMLUP00000005021	Sorting nexin 17.	Uncharacterized protein.	0.925
SNX17	VPS29	ENSMLUP00000001265	ENSMLUP00000014149	Sorting nexin 17.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.930
SNX17	VPS35	ENSMLUP00000001265	ENSMLUP00000012965	Sorting nexin 17.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.928
SNX17	VPS35L	ENSMLUP00000001265	ENSMLUP00000002678	Sorting nexin 17.	VPS35 endosomal protein sorting factor like.	0.953
SNX6	SNX17	ENSMLUP00000006437	ENSMLUP00000001265	Sorting nexin; Involved in several stages of intracellular trafficking.	Sorting nexin 17.	0.829
SNX6	VPS26A	ENSMLUP00000006437	ENSMLUP00000011518	Sorting nexin; Involved in several stages of intracellular trafficking.	VPS26, retromer complex component A.	0.927
SNX6	VPS29	ENSMLUP00000006437	ENSMLUP00000014149	Sorting nexin; Involved in several stages of intracellular trafficking.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.948