IL12RB2 protein (Myotis lucifugus) - STRING interaction network

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Score

IL12RB2

Interleukin 12 receptor subunit beta 2. (861 aa)

Predicted Functional Partners:

JAK2

0.983

IL27RA

0.975

JAK1

0.974

IL6

0.973

IL12RB1

0.967

G1NSF6_MYOLU

0.959

IFNG

0.957

LIF

0.948

TYK2

0.946

IL12B

0.932

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G1NSF6_MYOLU	IFNG	ENSMLUP00000000056	ENSMLUP00000002447	STAT_int domain-containing protein.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.939
G1NSF6_MYOLU	IL12B	ENSMLUP00000000056	ENSMLUP00000005803	STAT_int domain-containing protein.	Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.	0.655
G1NSF6_MYOLU	IL12RB1	ENSMLUP00000000056	ENSMLUP00000012559	STAT_int domain-containing protein.	Interleukin 12 receptor subunit beta 1.	0.939
G1NSF6_MYOLU	IL12RB2	ENSMLUP00000000056	ENSMLUP00000001298	STAT_int domain-containing protein.	Interleukin 12 receptor subunit beta 2.	0.959
G1NSF6_MYOLU	IL27RA	ENSMLUP00000000056	ENSMLUP00000011842	STAT_int domain-containing protein.	Interleukin 27 receptor subunit alpha.	0.709
G1NSF6_MYOLU	IL6	ENSMLUP00000000056	ENSMLUP00000014444	STAT_int domain-containing protein.	Interleukin 6.	0.883
G1NSF6_MYOLU	JAK1	ENSMLUP00000000056	ENSMLUP00000007075	STAT_int domain-containing protein.	Tyrosine-protein kinase.	0.987
G1NSF6_MYOLU	JAK2	ENSMLUP00000000056	ENSMLUP00000011617	STAT_int domain-containing protein.	Tyrosine-protein kinase.	0.986
G1NSF6_MYOLU	TYK2	ENSMLUP00000000056	ENSMLUP00000011245	STAT_int domain-containing protein.	Tyrosine-protein kinase.	0.986
IFNG	G1NSF6_MYOLU	ENSMLUP00000002447	ENSMLUP00000000056	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	STAT_int domain-containing protein.	0.939
IFNG	IL12B	ENSMLUP00000002447	ENSMLUP00000005803	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.	0.703
IFNG	IL12RB1	ENSMLUP00000002447	ENSMLUP00000012559	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Interleukin 12 receptor subunit beta 1.	0.938
IFNG	IL12RB2	ENSMLUP00000002447	ENSMLUP00000001298	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Interleukin 12 receptor subunit beta 2.	0.957
IFNG	IL27RA	ENSMLUP00000002447	ENSMLUP00000011842	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Interleukin 27 receptor subunit alpha.	0.917
IFNG	IL6	ENSMLUP00000002447	ENSMLUP00000014444	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Interleukin 6.	0.933
IFNG	JAK1	ENSMLUP00000002447	ENSMLUP00000007075	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Tyrosine-protein kinase.	0.967
IFNG	JAK2	ENSMLUP00000002447	ENSMLUP00000011617	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Tyrosine-protein kinase.	0.968
IFNG	LIF	ENSMLUP00000002447	ENSMLUP00000011463	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Uncharacterized protein.	0.487
IFNG	TYK2	ENSMLUP00000002447	ENSMLUP00000011245	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Tyrosine-protein kinase.	0.893
IL12B	G1NSF6_MYOLU	ENSMLUP00000005803	ENSMLUP00000000056	Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.	STAT_int domain-containing protein.	0.655