Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
BEST4Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (427 aa)    
Predicted Functional Partners:
RPE65
Retinoid isomerohydrolase RPE65.
      
 0.681
DEPDC1
DEP domain containing 1.
      
 0.681
CA7
Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family.
   
  
 0.680
G1QDN9_MYOLU
Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family.
    
 
 0.680
GLUL
Glutamine synthetase.
    
 
 0.680
OTOP2
Otopetrin 2.
   
  
 0.659
TTR
Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
      
 0.588
PELO
Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs.
 
      0.579
LGSN
Lengsin, lens protein with glutamine synthetase domain; Belongs to the glutamine synthetase family.
    
 
 0.548
RPL13
60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family.
      
 0.543
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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