Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AKR7A2Aldo-keto reductase family 7 member A2. (370 aa)    
Predicted Functional Partners:
NUP133
Nucleoporin 133.
   
 0.901
NUP107
Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).
   
 0.897
SEC13
SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.
    
 0.894
NUP85
Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC).
    
 0.851
SEH1L
SEH1 like nucleoporin; Belongs to the WD repeat SEC13 family.
    
 0.851
KCNH5
Potassium voltage-gated channel subfamily H member 5.
    
 0.833
G1PRB9_MYOLU
Uncharacterized protein.
    
 0.833
FAM83C
Family with sequence similarity 83 member C.
    
   0.822
DCTN2
Dynactin subunit 2.
    
   0.808
NCOA5
Nuclear receptor coactivator 5.
   
 0.799
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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