STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLK3Protein kinase domain-containing protein. (323 aa)    
Predicted Functional Partners:
ESPL1
Extra spindle pole bodies like 1, separase.
   
 0.979
CDC20
Cell division cycle 20.
   
 0.964
ITSN2
Intersectin 2.
    
 0.959
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.959
PPP4C
Serine/threonine-protein phosphatase.
   
 0.939
RAD21
RAD21 cohesin complex component.
   
 0.938
RAD21L1
RAD21 cohesin complex component like 1.
   
 0.938
INTU
Inturned planar cell polarity protein.
   
 0.931
SMC3
Structural maintenance of chromosomes protein.
   
 0.929
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.925
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.